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Gastroesophageal reflux disease (GERD) occurs when stomach acid frequently flows back into the tube connecting your mouth and stomach (esophagus). This backwash (acid reflux) can irritate the lining of your esophagus.

Many people experience acid reflux from time to time. GERD is mild acid reflux that occurs at least twice a week, or moderate to severe acid reflux that occurs at least once a week.

Most people can manage the discomfort of GERD with lifestyle changes and over-the-counter medications. But some people with GERD may need stronger medications or surgery to ease symptoms.



Common signs and symptoms of GERD include:

  • A burning sensation in your chest (heartburn), usually after eating, which might be worse at night
  • Chest pain
  • Difficulty swallowing
  • Regurgitation of food or sour liquid
  • Sensation of a lump in your throat

If you have nighttime acid reflux, you might also experience:

  • Chronic cough
  • Laryngitis
  • New or worsening asthma
  • Disrupted sleep

Risk factors

Conditions that can increase your risk of GERD include:

  • Obesity
  • Bulging of the top of the stomach up into the diaphragm (hiatal hernia)
  • Pregnancy
  • Connective tissue disorders, such as scleroderma
  • Delayed stomach emptying
  • Constipation

Factors that can aggravate acid reflux include:

  • Smoking
  • Eating large meals or eating late at night
  • Eating certain foods (triggers) such as fatty or fried foods
  • Drinking certain beverages, such as alcohol or coffee
  • Taking certain medications, such as aspirin


Endoscopy of the esophagus and the stomach (gastroscopy) will usually clarify if the condition is actually reflux and / or esophageal hernia. To rule out other diseases, it may be necessary to supplement with other examinations such as colonoscopy, ultrasound-, CT-, MRI scans or X-ray).

Read more about gastroscopy

Good advice

  • Lose weight if you are overweight - optimal BMI must be below 30
  • Stop smoking
  • Beware of fatty meals, chocolate, coffee, peppermint, fruit juice and alcohol
  • Don’t eat and drink the last 3 hours before bedtime
  • Avoid tight clothing
  • Bending forward worsen the symptoms. Kneel down instead.
  • Raise the head of the bed 5-10 cm with bricks under the bed-legs.
  • Constipation treatment

Medical treatment

The medical treatment is combined with the advice given above.

Antacids such as Link, Alminox, Novaluzid etc. all available over the counter, may in mild cases be sufficient treatment. The onset is within a few minutes and lasts only for approx. ½ hour. The effect can be enhanced by combining it with Gaviscon, which places a layer of foam above the contents in the stomach and thus reduces the backflow of acid into the esophagus.

If you have more severe symptoms, it is necessary to use acid-blocking medication that works by reducing acid output. There are different medications (Lansoprazole, Pantoprazole, Omeprazole), all of which are effective at reflux. The effect depends on the dosage and duration of treatment. These substances are very safe with a few and rare side effects even with prolonged treatment, and are therefore ideal for long term treatment.

Surgical treatment

In the majority of cases, medical treatment leads to significant improvements and often makes symptoms disappear completely. For patients with severe and chronic symptoms, surgery must be considered. Surgery is performed laparoscopic reinforcing the sphincter mechanism between the esophagus and stomach. You are usually discharged from hospital the day after surgery, and most people can resume normal activities within a few days. To achieve the best effect, BMI must be equal to or below 30.

Course of the disease

Reflux is often a lifelong condition where the symptoms can vary greatly. Most have shorter or longer periods with few or no symptoms. The most affected patients must constantly be in a high-dose acid-blocking therapy. The medicine reduces or eliminates symptoms and prevent complication but does not cure the condition. The only possibility of cure is surgery.

Complications of the disease

  • Prolonged ulceration and scar tissue can cause the development of stricture of the esophagus. The symptom is difficult swallowing. Mild cases of oesophageal hernia are treated with increased acid-blocking therapy. In severe cases it may be necessary to perform a balloon dilatation of the esophagus with a balloon lead down through the endoscopy equipment. Treatment is outpatient.
  • Many years of reflux can lead to a modification of the cells in the lower esophagus. The condition (Barrett's esophagus) is detected with tissue samples taken from the mucosa at the bottom of the esophagus. Barrett's esophagus may be associated with a slightly increased risk of developing malignant lesions. In order to control this condition, it must be monitored with outpatient endoscopy.

Monitoring reflux

For simple, uncomplicated reflux the condition is monitored by your general practitioner. It is not necessary with repeated endoscopy in these cases.

With the incidence of severe reflux or complications of reflux (ulceration, stricture, cell changes), a suitable control program that fits your case is agreed upon.

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Opdateret: 07 apr 2024 10:50
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